Problemi speciali
Parotite ricorrente giovanile: inquadramento clinico e approccio diagnostico-terapeutico
Juvenile recurrent parotitis: clinical overview and diagnostic-therapeutic approach
Diletta Giulia Giuntoli1, Anna Galletti2, Michela Pontrandolfo2, Serena Pastores
1SC di Otorinolaringoiatria e Audiologia, IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
2Scuola di Specializzazione in Pediatria, Università di Trieste
3Dipartimento di Pediatria, IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
Settembre 2024 - pagg. 443 -449 | DOI: 10.53126/MEB43443
Abstract
Juvenile recurrent parotitis is an uncommon condition characterised by recurrent episodes of parotid swelling that affects school-aged and pre-school children and shows a typical tendency to self-resolution during adolescence. To date, etiopathogenetic hypotheses and treatment options are still debated, as there are no current guidelines for its diagnosis and treatment so far. This article aims to provide valid recommendations for the management of children with recurrent episodes of parotitis and tips to identify cases worthy of further investigation and referral to the specialist.
Riassunto
La parotite ricorrente dell‘infanzia rappresenta una patologia non comune caratterizzata da episodi ricorrenti di tumefazione parotidea che interessa i bambini in età scolare e pre-scolare e che mostra una tipica tendenza ad autorisolversi durante l‘adolescenza. Ad oggi le ipotesi eziopatogenetiche e le opzioni terapeutiche sono fonte di dibattito, giacché la letteratura non dispone di linee guida univoche per la diagnosi e il trattamento. In quest’articolo vogliamo offrire indicazioni validate per la gestione dei bambini con episodi ricorrenti di parotite e suggerimenti per identificare i casi meritevoli di approfondimento e presa in carico da parte dello specialista.
Classificazione MeSH
Contenuto riservato
Per leggere l'articolo completo è necessario effettuare il login.
Non sei ancora registrato? Registrati
Bibliografia
1. Saarinen R, Kolho KL, Davidkin I, Pitkäranta A. The clinical picture of juvenile parotitis in a prospective setup. Acta Paediatr 2013;102(2):177-81. doi: 10.1111/apa.12004.
2. Capaccio P, Sigismund PE, Luca N, Marchisio P, Pignataro L. Modern management of juvenile recurrent parotitis. J Laryngol Otol 2012;126(12):1254-60. doi: 10.1017/ S0022215112002319.
3. Leerdam CM, Martin HC, Isaacs D. Recurrent parotitis of childhood. J Paediatr Child Health 2005;41(12):631-4. doi: 10.1111/j. 1440-1754.2005.00773.x.
4. Gellrich D, Bichler M, Reichel CA, Schrötzlmair F, Zengel P. Salivary Gland Disorders in Children and Adolescents: A 15-year Experience. Int Arch Otorhinolaryngol. 2020;24(1):e31-e37. doi: 10.1055/s-0039-1697993.
5. Wood J, Toll EC, Hall F, Mahadevan M. Juvenile recurrent parotitis: Review and proposed management algorithm. Int J Pediatr Otorhinolaryngol 2021;142:110617. doi: 10.1016/j.ijporl.2021.110617.
6. Saarinen R, Kolho KL, Lauhio A et Al. Herpes viruses lack association with acute parotitis in children. Pediatr Infect Dis J 2011;30 (12):1120. doi: 10.1097/INF.0b013e 31823247d4.
7. Vinagre C, Martínez MJ, Avendaño LF, Landaeta M, Pinto ME. Virology of infantile chronic recurrent parotitis in Santiago de Chile. J Med Virol 2003;70(3):459-62. doi: 10.1002/ jmv.10417.
8. Giglio MS, Landaeta M, Pinto ME. Microbiology of recurrent parotitis. Pediatr Infect Dis J 1997;16(4):386-90. doi: 10.1097/ 00006454-199704000-00010.
9. Hidalgo-Santos AD, Gastón-Téllez R, Ferrer-Lorente B, Pina-Pérez R, Oltra-Benavent M. Immune disorders associated with juvenile recurrent chronic parotitis. An Pediatr (Engl Ed) 2021;95(4):260-6. doi: 10.1016/j.anpede.2020.08.012.
10. Reid E, Douglas F, Crow Y, Hollman A, Gibson J. Autosomal dominant juvenile recurrent parotitis. J Med Genet 1998;35(5): 417-9. doi: 10.1136/jmg.35.5.417.
11. Ogden MA, Rosbe KW, Chang JL. Pediatric sialendoscopy indications and outcomes. Curr Opin Otolaryngol Head Neck Surg 2016;24(6):529-35. doi: 10.1097/MOO. 0000000000000314.
12. Bernkopf E, Colleselli P, Broia V, de Benedictis FM. Is recurrent parotitis in childhood still an enigma? A pilot experience. Acta Paediatr 2008;97(4):478-82. doi: 10.1111/j.1651-2227.2008.00678.x.
13. Faure F, Froehlich P, Marchal F. Paediatric sialendoscopy. Curr Opin Otolaryngol Head Neck Surg 2008;16(1):60-3. doi: 10. 1097/MOO.0b013e3282f45fe1.
14. Garavello W, Redaelli M, Galluzzi F, Pignataro L. Juvenile recurrent parotitis: A systematic review of treatment studies. Int J Pediatr Otorhinolaryngol 2018;112:151-7. doi: 10.1016/j.ijporl.2018.07.002.
15. Tucci FM, Roma R, Bianchi A, De Vincentiis GC, Bianchi PM. Juvenile recurrent parotitis: Diagnostic and therapeutic effectiveness of sialography. Retrospective study on 110 children. Int J Pediatr Otorhinolaryngol 2019;124:179-84. doi: 10.1016/j.ijporl. 2019.06.007.
16. Raquel Mendes A, Liane Moreira, Ângela Dias, et al. Recurrent parotitis in children - case series and literature review. Nascer e Crescer 2021;30:219-25.
17. González-Granado LI, Guillen-Fiel G. Recurrent parotitis: sialoendoscopy and botulinum toxin as alternatives. Indian J Dent Res 2012;23(4):554-5. doi: 10.4103/0970-9290. 104973.
18. Canzi P, Occhini A, Pagella F, Marchal F, Benazzo M. Sialendoscopy in juvenile recurrent parotitis: a review of the literature. Acta Otorhinolaryngol Ital 2013;33(6):367-73.
19. Antonucci L, Messia V, Nicolai R, De Benedetti F, Bracaglia C. Parotiti ricorrenti e linfopenia: un binomio da Reumatologia. Medico e Bambino pagine elettroniche 2020;23 (6):140 doi: 10.53126/MEBXXIIIG140.
20. Means C, Aldape MA, King E. Pediatric primary Sjögren syndrome presenting with bilateral ranulas: A case report and systematic review of the literature. Int J Pediatr Otorhinolaryngol 2017;101:11-9. doi: 10. 1016/j.ijporl.2017.07.019.
21. Guissa VR, Martinelli EL, Brandão LMKR, Garcia LD, Provenza JR, Mendonça JA. Sonographic evaluation of salivary glands in juvenile Sjögren’s syndrome. Acta Reumatol Port 2018;43(1):61-5.
22. Wu S, Shi H, Cao N, Ye L, Yu C, Zheng L. The correlation of immunologic derangement and juvenile recurrent parotitis: an investigation of the laboratory immunological observation. Acta Otolaryngol 2018;138
(12): 1112-6. doi: 10.1080/00016489.2018. 1515498.
23. Baszis K, Toib D, Cooper M, French A, White A. Recurrent parotitis as a presentation of primary pediatric Sjögren syndrome. Pediatrics 2012;129(1):e179-82. doi: 10.1542/ peds.2011-0716.
24. Bernkopf E, De Vincentiis GC. Parotite (o paroditite) ricorrente giovanile e malocclusione dentaria. Medico e Bambino pagine elettroniche 2008;11(9).
25. Nassimbeni G, Ventura A, Boehm P, Guastalla P, Zocconi E. Self-induced pneumoparotitis. Clin Pediatr (Phila) 1995;34(3):160-2. doi: 10.1177/000992289503400309.
26. Salehzadeh F, Molatefi R, Mardi A, Nahanmoghaddam N. Juvenile idiopathic recurrent parotitis (JIRP) treated with short course steroids, a case series study and
one decade follow up for potential autoimmune disorder. Pediatr Rheumatol Online J 2024;22(1):8. doi: 10.1186/s12969-023-
00946-0.
27. Berlucchi M, Rampinelli V, Ferrari M, Grazioli P, Redaelli De Zinis LO. Sialoendoscopy for treatment of juvenile recurrent parotitis: The Brescia experience. Int J Pediatr Otorhinolaryngol 2018;105:163-6. doi: 10. 1016/j.ijporl.2017.12.024.
28. Chandra SR. Sialoendoscopy: Review and Nuances of Technique. J Maxillofac Oral Surg 2019;18(1):1-10. doi: 10.1007/s12663-018-1141-0.
29. Wilson J 4th, Gorelik M, Gulliver J, Jaju A, Bhushan B, Rastatter J, Johnston D, Maddalozzo J. Superficial Parotidectomy for Juvenile Recurrent Parotitis. Laryngoscope 2023; 133(6):1495-1500. doi: 10.1002/lary.30349.
30. Moody AB, Avery CM, Walsh S, Sneddon K, Langdon JD. Surgical management of chronic parotid disease. Br J Oral Maxillofac Surg 2000;38(6):620-2. doi: 10.1054/bjom. 2000.0478.
31. van der Lans RJL, Lohuis PJFM, van Gorp JMHH, Quak JJ. Surgical Treatment of Chronic Parotitis. Int Arch Otorhinolaryngol 2019; 23(1):83-87. doi: 10.1055/s-0038-1667006.
Corrispondenza: dilettagiulia.giuntoli@burlo.trieste.it